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Cette série met en scène Cathy Jamison, une femme menant une vie banale avec un époux immature et un fils adolescent dont l'existence va être chamboulée lorsqu'elle apprend qu'elle souffre d'un cancer au stade 4. Elle bouscule alors ses habitudes et décide de profiter du peu de temps qui lui reste à vivre en faisant ce qu'elle s'interdisait auparavant
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